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NL888 Posted 12 years ago
Grammar

Whose maturity is clear from a rearrangement that its genes undergo during development?

1) Does "whose maturity is clear from a rearrangement that its genes undergo during development" mean "whose maturity
can show clearly after a rearrangement that its (T cell's) genes go through (the rearrangement)"?

2) What does rearrangement mean here?

Context:

To convince sceptics, Obokata had to prove that the pluripotent cells were converted mature cells and not pre-existing pluripotent cells. So she made pluripotent cells by stressing T cells, a type of white blood cell whose maturity is clear from a rearrangement that its genes undergo during development. She also caught the conversion of T cells to pluripotent cells on video. Obokata called the phenomenon stimulus-triggered acquisition of pluripotency (STAP).
  

Top answer

No. He had to prove that the cells were mature before he stressed them. As the T-Cells mature and develop, their genes change by rearranging (rearrange = assemble in a different sequence) themselves.

  • No.
  • He had to prove that the cells were mature before he stressed them.
  • As the T-Cells mature and develop, their genes change by rearranging (rearrange = assemble in a different sequence) themselves.
  • The "adult pattern" of the T-cell genes is different from the pattern they had when the cells were pluripotent.
  • So if the new pluripotent cells have this "adult pattern", it proves that the cells were not pluripotent before the stressing.
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3 Answers
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No.

He had to prove that the cells were mature before he stressed them.

As the T-Cells mature and develop, their genes change by rearranging (rearrange = assemble in a different sequence) themselves. The "adult pattern" of the T-cell genes is different from the pattern they had when the cells were pluripotent. So if the new pluripotent cells have this "adult pattern", it proves
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Thank you.

But I failed to understand " if the new pluripotent cells have this "adult pattern"".
How could a pluripotent cell have the adult pattern? I know you've put the adult pattern" into the quotation marks. But I could not got it.
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NL888But I failed to understand " if the new pluripotent cells have this "adult pattern"".
The author is not clear on that point. She only says that the cells she starts with have the adult pattern. She makes no claim about the cells retaining this pattern after being stressed.

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