". This can be used without any connotations beyond what it actually says, or colloquially it can be used to stall or avoid answering a question when you're not sure of the motives of the person asking, or don't know who they are (in which case, depending on the tone of voice, it may not be terribly polite). It can also be used when information is available or being offered, and you're asking who is interested in knowing that information.
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AvangiMr. Wordy has just about covered it, but I'm not sure whether or not the "extremely" rude meaning is included