I am going to see my uncle is sick.
I am going to see my uncle, who is sick.
Please check them.
Hi - I am going to see my uncle. The above is good. However, once you introduce the idea of 'is sick', you have created a subordinate (or dependent) clause with its own verb ('is').
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Hi
- I am going to see my uncle.
The above is good. However, once you introduce the idea of 'is sick', you have created a subordinate (or dependent) clause with its own verb ('is'). It relates to the uncle and you need a linking word: it is 'who' and you have done that correctly in your second sentence
The first one is incorrect. You can, if you wish, avoid the subordinate a