1) I don't want to speak to you again.
2) I don't want to speak with you again.
The question of the difference between "speak to" and "speak with" comes up frequently. q=difference+between+speak+with+and+speak+to
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The question of the difference between "speak to" and "speak with" comes up frequently. See e.g.:
https://www.EnglishForward.com/search/speak%20with%20speak%20to.htm
htrek1) I don't want to speak to you again.
If someone did something to make you really mad, you can use # 1.
2) I don't want to speak with you again.
I spoke to /with the owner of the apartment yesterday about the possiblility of reducing the rent. He said, he could redu
htrek1) I don't want to speak to you again.
This is British English.
htrek2) I don't want to speak with you again.
This is American English.