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NL888 Posted 13 years ago
Grammar

What does " targeted decolonization" mean?

Esp. what is decolonization?

Context:

Background

Both targeted decolonization and universal decolonization of patients in intensive care units (ICUs) are candidate strategies to prevent health care–associated infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA).

Methods

We conducted a pragmatic, cluster-randomized trial. Hospitals were randomly assigned to one of three strategies, with all adult ICUs in a given hospital assigned to the same strategy. Group 1 implemented MRSA screening and isolation; group 2, targeted decolonization (i.e., screening, isolation, and decolonization of MRSA carriers); and group 3, universal decolonization (i.e., no screening, and decolonization of all patients). Proportional-hazards models were used to assess differences in infection reductions across the study groups, with clustering according to hospital.

More:
http://www.nejm.org/doi/full/10.1056/NEJMoa1207290?query=featured_home
  

Top answer

MRSA lives in the sinuses of an infected person even if it isn't doing anything at the moment. It is said to colonize a person thus. "Decolonization" seems to mean "eradicating the MRSA colony in a person".

— Enoon

  • MRSA lives in the sinuses of an infected person even if it isn't doing anything at the moment.
  • It is said to colonize a person thus.
  • "Decolonization" seems to mean "eradicating the MRSA colony in a person".
  • "Targeted" means treating only patients with proven MRSA colonies, and "universal" means treating everybody who comes through the ICU, regardless.
  • I am not a doctor.
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1 Answers
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MRSA lives in the sinuses of an infected person even if it isn't doing anything at the moment. It is said to colonize a person thus. "Decolonization" seems to mean "eradicating the MRSA colony in a person". "Targeted" means treating only patients with proven MRSA colonies, and "universal" means treating everybody who comes through the ICU, regardless.

I am not a doctor.
0

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