In an exclamatory or declamatory sentence it is possible. "What dreams I had! " There is not enough of your sentence to tell whether it makes sense.
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arismaestart a sentence with the word "what"Yes, that's possible. The grammatical pattern called a pseudo-cleft can start a sentence:
CalifJimThe grammatical pattern called a pseudo-cleft can start a sentence:Thanks for that information, teacher.
CalifJimWhat you need is a warm coat.What they forgot was the spoon.What Jake wanted was a sports car.Could you please tell me what other things we could use in that structure? For, can we say these, please?
LaboriousWhat you need is to go there.This is the only one of the three that's possible.