Usage of virtual and in itself

I have learned that the word virtual have opposite meanings in itself, but I do not think they are different and opposite.

1. very nearly a particular thing:

2. made, done, seen etc on the Internet or on a computer, rather than in the real world:

In the end, they originated from the same logic, I think. What do you native English speakers think?

And which sentence is natural and correct?

The word virtual have opposite meanings in itself.

The word virtual have opposite meanings in it.

Thank you so much as usual and have a good and safe day.