1. The use of knife can be handy. You need the indefinite article: The use of a knife can be handy.
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mekkalompTo my understanding, the difference between sentence 1 an
mekkalomp1. The use of knife can be handy.2. Using the knife can be handy.Neither of these sounds right. The basic concept of a "use" or "using" being "handy" is not natural. "The use of knife" also needs an article (or other determiner) for "knife".
mekkalomp1. The members of team Bad