It would normally appear informally, I imagine, but I think 'to be short' could be used anywhere.
However, to clarify:
A: I am a little short of money, so I can't buy this book.
B: How short are you?
A: I'm short (by) $2.00.
'Short of' indicates the material from which some quantity is deficient.
'Short (by) indicates the quantity deficient.