The situation in which you are envisaging saying "it's nothing special to notice" is not immediately obvious to me. "there's nothing special in/to noticing" seems to mean that the ability to notice things is common or normal, but I wonder whether that is really what you want to say. I think more context is needed.
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Mathiashm"there's nothing special in noticing that" + clause"it's nothing special to notice that" + clauseBoth patterns are correct. Personally, I would probably use the first.
MathiashmThe question is basically about "something special" + to or in notice/-ing.In the right context, three of the four combinations are possible: