It can. " "Do" is the "tonal center" in the diatonic major and the diatonic minor scales. "Do - Re - Mi" are the "first three" steps of the diatonic major scale.
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AnonymousDo "Do, Re, Mi" correspond to middle C, D, E on the piano?Only in some European systems. A French Symphonie en re mineur would be in English a Symphony in D Minor.