Hi, RekTerFig. Welcome to EnglishForward. I assume you are looking for a word to put in the blank, but your sentence as a whole doesn't make sense.
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RekTerFig the harmful ... of poor pollution leads to illnessIt's my guess: The harmful air/environment/water pollution leads to poor health and illnesses.
Anonymous It's my guess: The harmful air/environment/water pollution leads to poor health and illnesses.You might be right.