The child had gone home. Meanwhile, his mother was searching for him in the streets. The child went home. Meanwhile, his mother was searching for him in the streets. The child went home. Meanwhile, his mother had been searching for him in the streets.
What is a difference between the sentences?-- In #1 the child went home first; in #3, the searching
Meanwhile, Eads had suffered a severe recurrence of the tuberculosis which periodically incapacitated him throughout his adult life, and-as indicated earlier-had retired from active work.
Meanwhile, Eads suffered a severe recurrence of the tuberculosis which periodically incapacitated him throughout his ad
You need to use #1 simply because the the final verb ('had retired'), which occurs at the same time or after recurrence, is in past perfect. Otherwise, you have presented no context that legislates for either verb form.