I think however is normally followed by the contrasting part, not preceeded by. : * I'ts nothing serious though * However, it's nothing serious. But I could be wrong..
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wangqh2696122Harry, would you ___ the story where John left off yesterday?
A. pick up B. take up "Take up" is sometimes used in this case, but I think of it as applying to some sort of action.
"Let's take up the agenda where we left off."
By the same token, "pick up" is sometimes used in my example.