Informally it is OK, meaning to swallow a large quantity of something at once (or make the muscle movements as if doing so).
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messier42 Thank you. In what states of feeling do you use this? When shocked ?I thought of someone literally swallowing something. E.g., said to a child who had to take some medicine, "Take a big swallow!"
AnonymousThe implication is of a threatening situation, like if you're being forced to drink a lot of something you don't want to drink.I don't use it that way. There is no force involved.