It's most often "take slight at" or "feel slighted by/at". These are equivalent to "take offense at" and "feel offended by/at". - I took it slightly at/for what he said.
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rainspeakerOne thing that has not been mentioned is slight as a noun.I don't think you mean this. What part of speech did you think "slight" was in the expression "take slight"? It's a noun.