Read: pharmacologically-active metabolite s metabolite s is a NOUN but you seem to have understood that. Now, moving to your question. See this example: Many people have umbrellas whose color is red .
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Marius HancuMany people have umbrellas whose color is red.A simple and good example!
I don't find anything strange about it. You're talking about a common property to all those umbrellas, color. You shouldn't say colorS.
Same in your example, production.