yes
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BenitaYou could even say 'What is your opinion about my first question?'And that would be better, IMO. "How about" is a bit impolite in this context, as I see it, it's like asking "Why haven't you provided your opinion by now?"
Tidus"How about your opinion on my first question".http://dictionary.cambridge.org/define.asp?key=55695&dict=CALD