He is the only responsible person for the job.
He has also a responsibility to the job.
Correct?
I don't know what you mean. There is one person who can do the job - Mr. Matthis.
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I don't know what you mean.
There is one person who can do the job - Mr. Matthis.
This job / task is Mr. Matthis' responsibility.
Getting this job done is Mr. Matthis' responsibility.