Only the second is possible, but 'regard', not 'regards'. However, this is also worth reading: 'Although sometimes considered poor substitutes for about or concerning , the phrases as regards, in regard to, and with regard to are standard and occur in all varieties of spoken and written English, especially in business writing: A s regards your letter of January 19 . … In regards to, and with regards to are widely rejected as errors.
New words, one handy idiom, and a 2-minute quiz — delivered to your inbox to keep your streak alive.