There is a distinct difference between /k/ and /kw/ to a native speaker. I know several people from Pakistan and from India, and I've never noticed a difficulty on their part to pronounce them differently.
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Mr. TomFor Pakistanis, coat and quote have exactly the same pronunciation.You must do whatever you can to make them stop it!
CalifJimThey may also have difficulty with a combination of front glide and front vowel, such as in yeast, perhaps saying it as east.Absolutely right CJ,