` Consider 'fatso' to be always offensive, even among close friends and family. It's not a function of this forum to provide lists of hurtful slang terms for people to upset and embarrass others with. Rover
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AnonymousIf you know the person well, the following might be almost an affectionate nickname or a term of endearment,Believe it or not, this parallels with my native language :-)
AnonymousAn affectionate nickname: slim.