Need Suggestions to improve my SOP for PhD

To whom it may concern,
The enigma of life, the complex interlinking of genes and proteins in an organism, fascinates anyone taking the time to explore it. One of my favourite questions, I used to ask myself and fellows in the freshman year of college during casual conversation usually elicits a puzzled look: how could these molecules/ components, though very small in size, could perform heavy load of working a well -planned manner and that too within a fraction of second? My curiosity and question asking nature and the imaginary world of DNA and Protein led me to pursue my higher education in biological science.
Later, I enrolled at University of XXX to pursue a degree in biotechnology, where I felt that I could unleash the biologist inside me on my broader. As an undergraduate, I have worked on both prokaryotic and eukaryotic systems, eventually finding my niche in studying the mechanism behind DNA replication, gene expression, protein synthesis and the principle behind that how cells makes own processes drive regeneration of damaged or diseased tissue. My insatiable thirst for delving deep into these subjects coupled with my profound aptitude for research in cell and molecular biology has inspired me to pursue a graduate career at XXX University.
During my master studies in cell and molecular biology, I joined the reputable Unit of Functional Pharmacology, Department of Neuroscience at XXX University and was privileged to work under the supervision of Dr.XXX. In 2011, the unit received the highest ranking as “top international class” by an external international panel evaluation of XXX University (KoF2011) stating, “The research output of this group is exceptional.” Here I was involved in project titled “Functional and histological characterization of glutamine transporter like protein (TMEM104) in the central nervous system of mice.”, Where my mentor taught me how to characterize a protein regarding expression pattern and cellular specificity by using techniques like in situ-hybridization and immunohistochemistry on tissue sections from mice, neuronal cell-lines and neuronal primary cultures. During the project, I also analysed histological sections from brains where I labelled subtypes of neurons and analysed the distribution of expression of TMEM104 in relation to known neuronal markers. I also worked on an additional project breeding chimeric mice which had been generated from embryonic stem-cells with a related putative glutamine transporter floxed. The aim of the project was to obtain stable germ line transmission of the transgene to obtain a conditional knockout line of this transporter. Beside these two projects, I also worked on a project titled, ‘Localization and gene expression of CTPS2 Protein in adult mouse brain’ by performing qPCR and western blotting. From my research work, I got a glimpse of the rigorousness lab work along with the anxiety of anticipation, the pure exhilaration of a positive result. This has further strengthened my dream and desire to be a part of a prestigious world renowned university where I can take challenging problems and contribute to the latest research going in the field.
Molecular biology is immense and fast growing field of science useful to both the individual and society. Various diseases among the people in my geographical area like hepatitis, cystic fibrosis, sickle-cell disease, cancer, need to be molecularly characterized. To be a useful, productive scientist, I must pursue higher education in the field of molecular biology. To me, Molecular biology is not just a tool that benefits an individual, but also the community and society at large. And I hope to equally make myself useful, as well as further develop my career in science.

With respect to my current research interests, I think that the cancer epidemiology program at the Department of XXX, XXX Institute is ideal for what I would like to study. It has a long tradition of teaching and research in the epidemiology of cancer, especially with well-grounded multidisciplinary research and cutting-edge methodology which will allow me not only to study the reasons for the cancer’ pathogenesis, development and distribution among certain groups of people but also learn how to formulate policies and measures to prevent, control and eliminate cancer-related diseases. I believe that cancer epidemiology is the most probable approach to unravel cancer etiology. The applied nature of epidemiology makes it highly valuable in providing guidance and directions for basic research. Furthermore, cancer epidemiology takes a group perspective in combating cancer, either a family group or the entire mankind can benefit macroscopically from its research findings. Finally, promotion of human health through disease prevention is always more positive and economically meaningful than post-contraction therapy.

Sincerely,