Friends, <br/><br/>When and what does "thumps-up" sign refer to? <br/><br/>According to me, we use it to mean : <br/>1) Best of Luck. <br/>2) Got it (Success). <br/><br/>I couldn't understand it's usage in this sentence. <br/>Context : "Giving a THUMPS-UP sign to stem cell research works...." <br/><br/>Praveen.