Can you guess what they are talking about?
What can you guess they are talking about?
Is there any meaning difference between them?
Hoony Is there any meaning difference between them? The second one is not a good sentence. It's hard to say what it means — if it means anything at all.
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HoonyIs there any meaning difference between them?
The second one is not a good sentence. It's hard to say what it means — if it means anything at all.
That pattern only seems to work with "think":
What do you think they are talking about?
In this form it is similar in meaning to the first sentence.
CJ