'Make' hear means "accomplishing, to achieve a goal". So, if it is rewritten, it could mean "We're never doing to do it!". It could be one person suggested climbing Mount Everest, and his friend, being realistic could say "Hah, we are never going to make it to the top.".
I am not quite sure I understood what do you mean by this question. However there many meanings to "make" yuo can choose one ?
Never going to do it Never going to solve it Never going to complete it Never going to accomplish it Never going to achieve it Never going to perform it