Hi. English is not my mother-tongue and I have a lot of problems with grammar, which when I was 7, I used to say "grandma". I have a question regarding "this" and "that". And "the" too

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I want to share a person's photo on my facebook timeline and tag a friend of mine because it seems like she is in the photo. Do I write:
A. "Isn't THAT you in THE picture?"
B. "Isn't THIS you in THE picture?"
C. "Isn't THAT you in THIS picture?"
D. "Isn't THIS you in THIS picture?"
I would really appreciate your help. Thank you.