Yes. It's called the vocative comma, and it sets off the person or persons you're addressing.
New words, one handy idiom, and a 2-minute quiz — delivered to your inbox to keep your streak alive.
goronsky'Go, me!' or 'Go, Yankees!'The comma looks wrong to me. This seems different from examples like Go (now), John.
goronsky'Go, Yankees!', is the comma required in each?Yes, unless you're trying to turn "go" into a transitive verb, and that would be pretty strange.