Is the comma here necessary?

Question

"UniQure's hemophilla B treatment appears to be among the treatments working, with 52 of 54 patients no longer needing injections of factor IX after 6 months in its latest study."

Q1. Is the comma here necessary?

Q2. Is "working" modifying "treatments" ? If so, why doesn't it come before "treatments" like "the working treatments"?

Q3. what does "working" mean here? "effective" or "working" is a chunk as "working with 52~"?

Anonymous · Accepted Answer

thanks3 Q1. Is the comma here necessary?

Yes. Otherwise, the reader sees "treatments working with patients".

thanks3Q2. Is "working" modifying "treatments" ?

Yes.

thanks3why doesn't it come before "treatments" like "the working treatments"?

It might have just as well. There might be a reason in the surrounding text for the difference. Also, it means "the treatments that are working", which is more what is meant than "one in the list of efficacious treatments."

thanks3Q3. what does "working" mean here?

Efficacious, having the desired medical effect on the disease, which I have to guess is hemophilia and not hemophilla.

thanks3"working" is a chunk as "working with 52~"?

No. 'With" as with all the old, short words, has a zillion uses. Here is an applicable definition for this one, or at least one that is not too far from the sense:

preposition - 5. "in or according to the experience or practice of - with many of us, our ideas seem to fall by the wayside— W. J. Reilly" ( https://www.merriam-webster.com/dictionary/with )

Is the comma here necessary?

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