irregardless and regardless

Irregardless is just a 'non standard' form of regardless. It's best to stick to using regardless.

I ran down the street regardless of the fact that I was naked.

My personal (American) point of view: Banish irregardless from your memory right now.

Here's your sentence: Regardless of how often you hear others use it, irregardless "is thoroughly and consistently condemned."

There are other points of view, but I hold that one. (The site I just quoted goes on to say: "The level of abuse hurled at the poor thing is astonishing

In my opinion, the difference is very simple.

regardless is one of the words of the English language.
irregardless is not.

CJ

I clicked this thread to see something illuminative, but bursted into laugh. My stomach's still aching now caused by that good laugh.

We have an expression for that in English (in the U.S., anyway):

I split a gut (laughing)!

(Extremely informal.)

CJ

The word" Regardless" is often combinated with prep " of"

"irregardless" is nonstandard English for "regardless". It is consistently condemned, as Grammar Geek says, so you should not use it.

Having said that, I'm not why it is condemned. It is a word that is commonly used (otherwise there wouldn't be such a fuss over it) and there isn't anything wrong with it, from a linguistic point of view.