No. These are: She lost her mother, which worsened her bipolar disorder. She lost her mother, which made her bipolar disorder worse.
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Aspara GusNo. These are:She lost her mother, which worsened her bipolar disorder.She lost her mother, which made her bipolar disorder worse.I agree that these are much clearer than the original.
Aspara Gus[The loss of her mother / Her mother’s death] has [made her bipolar disorder worse / worsened her bipolar disorder].A p
fivejedjonA pedant might object that these two have the same potential ambiguity as the first - the her before mother' could refer to the same person as the her before bipolar.This did occur to me, but I let it pass, since it’s a very unlikely misinterpretation. On second thought, though, I would prefer your suggestion.