And of course Lucy was the prime suspect.
Should it be punctuated like-
And, of course Lucy was the prime suspect.
And, of course, Lucy was the prime suspect.
And of course Lucy was the prime suspect.
When you are writing what is being said during an interview.
guava walk 940 And, of course, Lucy was the prime suspect. This is my preference.
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guava walk 940And, of course, Lucy was the prime suspect.
This is my preference.
Depending on the context, an alternative approach might be to use a lower-case 'and' to join this to the previous sentence.