It's very interesting. because in Arabic Language, If there are 10000000 women, and only one man in a society or community, one should use pronoun and verb in masculine form. Of course, I am Iranian.
Everything depends on the context. However, it is quite acceptable to use both she and he, I deem. As long as grammatical category of gender in the English language doesn't differentiate between masculine and feminine genders, it is possible to use both. In fact, in Old English, as far as I know, there were three genders. However, in the course of history opposition of genders disapp