Just don't do any activity that the outcome of that activity will blow you after 1 year
Is that sentence correct if not so please make it correct. I just telling him that not to do such work.
What do you man here by 'blow you'?
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Just don't do any activity that will ruin your chances of getting ahead.
Just don't do any activity that will result in ruining your health.
The idiom is 'blow it', not 'blow you'. "it' refers rather vaguely to the situation or whatever we are talking about.
eg I had a great job, but I blew it.