culture') is the object of the preposition. There works as the expletive in non-finite clauses, too. Compare: 'There's no use in his being obstinate'.
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Mister MicawberThe two 'that's are correct but a bit awkward, so I'd like to eliminate one of them. It would be OK if you did this:Thanks
The investigations of many psychologists and anthropologists support the generalisation that there is little significantly different in the underlying mental processes manifested by people from different cultures.