Fine, but be sure to precede it with a comma.
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Her sister will be coming to the meeting, however.'
Just wondering, would ending a sentence in formal contexts be just as fine as well?
Yes, that is fine.
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AnonymousEmma can't come to the library; however, her sister will be attending the meeting.This is indeed the recommendation of many style manuals, but in practice the advice is probably more often disregarded than observed.