I understand "driven on to the margins" to mean driven to the edges of the land that they once occupied.
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Anonymousthey were forced to leave the center and settle in border lands; in order to decrease their influenceThat's an interpretation, not a paraphrase.
AnonymousNative populations were exterminatedAll of the native people were killed.
Anonymousdriven on to the marginsThey were forced from the range of territory they once occupied. They had to live on small, marginal areas. ("Margins" implies the least productive or poorest land.)