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NL888 Posted 13 years ago
Grammar

Does " tumor cells mainly generating energy" mean ...?

Does " tumor cells mainly generating http://en.wikipedia.org/wiki/Energy by nonoxidative breakdown of http://en.wikipedia.org/wiki/Glucose" mean "tumor cells which are mainly generating enegy through nonoxidative breakdown of glucose"?

Context:
In 1924, Warburg hypothesized that http://en.wikipedia.org/wiki/Cancer, malignant growth, and http://en.wikipedia.org/wiki/Tumor growth are caused by tumor cells mainly generating http://en.wikipedia.org/wiki/Energy (as e.g. http://en.wikipedia.org/wiki/Adenosine_triphosphate / ATP) by nonoxidative breakdown of http://en.wikipedia.org/wiki/Glucose (a process called http://en.wikipedia.org/wiki/Glycolysis) and the subsequent recycling of the metabolite http://en.wikipedia.org/wiki/NADH back to its oxidized form, for reuse in the glycolytic cycle to complete the process (known as http://en.wikipedia.org/wiki/Fermentation_(biochemistry), or http://en.wikipedia.org/wiki/Anaerobic_respiration). This is in contrast to "healthy" cells, which mainly generate energy from oxidative breakdown of http://en.wikipedia.org/wiki/Pyruvate. Pyruvate is an end product of http://en.wikipedia.org/wiki/Glycolysis, and is http://en.wikipedia.org/wiki/Oxidized within the http://en.wikipedia.org/wiki/Mitochondria. Hence, and according to Warburg, cancer should be interpreted as a http://en.wikipedia.org/wiki/Mitochondrial dysfunction.

MOre:
http://en.wikipedia.org/wiki/Otto_Heinrich_Warburg
  

Top answer

The wording in the article more clearly states that the abnormal process of energy generation is a cause of the cancer (rather than just being a concurrent process).

  • The wording in the article more clearly states that the abnormal process of energy generation is a cause of the cancer (rather than just being a concurrent process).
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1 Answers
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The wording in the article more clearly states that the abnormal process of energy generation is a cause of the cancer (rather than just being a concurrent process).

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