You can.
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goronskyI need to ask my wife, Jennifer.This sentence is ambiguous with or without the comma. If you are addressing Jennifer and she is not your wife, then a clear versions is: Jennifer, I need to ask my wife.
Yes.
goronsky: Can I omit the comma in these too
My brother Frank was there. (I have 1 brother.)
My friend Jamie hates gossip. (I have only 1 friend.)
My best friend Lou passed away. (I have only 1 best friend.)
goronsky:
This:
My wife Debby, my daughter Samantha and my son Ted will be there. (
Aspara GusI thought she was his wife, since the original post clarifies "I'm not speaking to Jennifer. I am going to ask her something".It's not clear to me who 'her' is in: " I'm not speaking to Jennifer; I am going to ask her something". It seems as though he is not speaking to Jennifer at the moment, but he is going to speak to her, to ask her something.