Either then 'placements' being plural for #2, what is the dfiference in meaning between these two? Does it matter which one I say? They seem to have the same meaning?
1. A perfect placement is difficult at the best of times.
2. Perfect placements are difficult at the best of times.
They carry the same meaning without a context. Number 1 is a bit more 'pointed', i.e., would tend to be said for a specific incident. Number 2 might be said in a given incident, too, if the point of saying it was to characterize the incident as a general type of incident.