Both answers are ok in conversational English. Purists want you to reserve "like" for its uses as an adjective and adverb (or, for many speakers today, a preposition). " In fact, purists would like you to say: Don't talk to me as if you WERE talking to a friend, for you are not my friend.
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alc241 Don't talk to me as if you're talking to your friend, I'm not your friendBoth are correct, But I would choose the first one, which seems to me much more formal that saying ( Like ).
2 Don't talk to me like you're talking to your friend.