This is a dictionary question. You can answer it by visiting an online dictionary such as dictionary.com. Here are some definitions of artefact/artifact from dictionary.com:
1. something made or given shape by man, such as a tool or a work of art, esp an object of archaeological interest 2. anything man-made, such as a spurious experimental result 3. cytology: a structure seen
They are alternative spellings of the same word, which is quite common. Here are a few examples:
...Code 46 connotes uneasiness about -- not uncritical celebration of- transnational relocation of a cultural artefact. Certainly, the spectator who comes to Code 46 after first viewing The Claim... ...Archaeological traditions need not always be equated with ethnic groupings. i