An unnecessary comma

Question

The importance of the fast-moving stream of events in our modern world makes it imperative that we be well informed. Significant social, economic, and political issues, all demanding serious and open-minded investigation, require more than ever before a higher level of reader enlightenment.

Many grammar book say even though the subject phrase so long, we can't use a comma between a subject and verb.
In the sentence above, How can the comma before 'require' be accounted for?

Thank you in advance for your help.

GPY · Accepted Answer

The comma before "require" is the second of a pair of commas enclosing the parenthetical phrase "all demanding serious and open-minded investigation".

Park sang joon · Answer

Thank you, GPY, for your answer

GPY The comma before "require" is the second of a pair of commas enclosing the parenthetical phrase "all demanding serious and open-minded investigation".

I have seen some is used as parenthetical phrase in the structure that a couple of phrases become one part several times.
As I have thought every phrase is equal in terms of importance whenever I see the sentences including such a structure like my example, I can't always notice a parenthetical phrase

GPY · Answer

Probably you already understand this, but the meaning is like:

Significant social, economic, and political issues, all of which demand serious and open-minded investigation, require more than ever before a higher level of reader enlightenment.

Park sang joon · Answer

Thank you, GPY, for your very helpful accounts

GPYSignificant social, economic, and political issues, all of which demand serious and open-minded investigation, require more than ever before a higher level of reader enlightenment.

I have had wrongly understanding; I'm such a fool.
Once more, Thank you for your providing me with enlightenment.

An unnecessary comma

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