Hi Maple, In this context, "aggressive" implies risk of certain degree. To me, it infers negative connotation, and has no relevence with being "comprehensive". In finacial terms, if I say I have an "aggressive inverstment porfolio", I mean exposure to certain volatility of monetary gain and loss which simply means "risk".
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MapleAccording to this theory, even distant metastases are the result of direct extensions of local involvement (affecting the breast, the chest wall, axillary and supraclavicular lymph nodes, or any combination of the sites). The Halstedian approach thus dictated that aggressive local therapy for control of disease in the breast, chest wall,