It could mean almost anything. Someone is arranging a date for him on the weekend, and he has to go make a phone call to get information about her or about the date. He is hiring a model for a life drawing class, or an actress for a commercial, or somebody to walk his dog.
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DelmobileNot for this gal. The only euphemism like that I know is "I have to go powder my nose" and I don't think anyone's actually said it for fifty years.I haven't heard it recently either, I guess. Do today's women still use powder in their makeup?